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Vardenafil is a phosphodiesterase-5 inhibitor, a drug used to treat erectile dysfunction. Vardenafil dilates blood vessels of the penis during sexual arousal, resulting in increased blood flow to the penis and stable erection. Vardenafil generic is made by the pharmaceutical company Sunrise Remedies. Vardenafil brand is made by Bayer.

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- Product Description
- Side Effects
- Safety Information
Drug name: Vardenafil
Therapeutic effects:
Vardenafil blocks PDE-5 that causes breakage of cGMP. As a result, the action of endogenous NO in the cavernous bodies during sexual stimulation is enhanced. The result is relaxation of smooth muscles of cavernous bodies, which increases blood flow to the penis and causes natural erection.
After intake, Vardenafil is quickly absorbed and starts to act within 15-25 minutes, duration of action is 4-5 hours.
Indications:
Erectile dysfunction
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Side-effects:
- Headache, dizziness, blurred vision, drowsiness, high muscle tone
- Dyspepsia, nausea, increased GGT
- Hot flushes, hypertension, syncope, myocardial ischemia, nasal bleeding
- rhinitis, dyspnea
- Anaphylactic reaction (including laryngeal edema), photosensitivity
- Myalgia, back pain
- Glaucoma
- Priapism
Drug interactions:
Vardenafil is known to interact with the following drugs:
- Antifungals
- Histamine H2-receptor antagonists
- Antiretroviral drugs
- Nitrates
- Alpha blockers
- Other ED drugs
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Cautions and restrictions:
Vardenafil is not recommended for use in patients with the following conditions:
- Myocardial infarction or stroke (in the past 6 months)
- Very low blood pressure (systolic blood pressure at rest below 90 mm Hg. Art.)
- Uncontrolled high blood pressure
- Unstable angina
- Congenital prolongation of QT interval
- Aortic stenosis and idiopathic hypertrophic subaortic stenosis
- Severe liver failure
- End-stage of renal failure requiring dialysis
- Inherited retinal degenerative diseases (eg, pigmentary retinopathy)
- Anatomical deformation of the penis (cavernous fibrosis, Peyronie's disease)
- Diseases predisposing to priapism (sickle cell anemia, multiple myeloma, leukemia)
- Tendency to bleeding and exacerbation of peptic ulcer disease
- Hypersensitivity to any component of Vardenafil
Vardenafil is not indicated for women and children aged below 16.
Additional information:
Store the drug in a dry place at temperature not above 30 ° C. Shelf life - 3 years.
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